Toxic and drug-induced liver injury Irena Jankowska, Krzysztof Jankowski, Jakub Kmiotek, Joanna Pawłowska, Jerzy Socha Medical Science Review - Hepatologia 2007; 7 32-41 aaICID: 485981
Article type: Review article
IC™ Value: 2.88
Abstract provided by Publisher
Drugs cause a variety of forms of liver injury that range in severity from trasient, asymptomatic elevations in serum aminotransferase activity to acute hepatic failure. The diagnosis is frequently difficult because of the absence of specific signs in most cases and mainly relies on the exclusion of other causes, expecially viral infections. The diagnosis should be considered particulary in older patients who take many drugs together.
In this article we provide information on the detection, evaluation, diagnosis and management of drug-related hepatototoxicity.