Diagnosis and treatment of non-alcoholic fatty liver disease in children Dariusz Marek Lebensztejn, Piotr Socha Medical Science Review - Hepatologia 2010; 10 95-100 aaICID: 911695
Article type: Review article
IC™ Value: 3.34
Abstract provided by Publisher
Non-alcoholic fatty liver disease (NAFLD) seems to be the most common liver disease and it appears to be an important cause of liver failure in adulthood. Diagnostic criteria are based on liver histology which may lead to some diagnostic dilemmas in every day practice. Other diseases that cause fatty liver should be excluded in differential diagnosis. The value of surrogate markers of NAFLD like ultrasound and MRI was discussed. The role of obesity and obesity-related metabolic disturbances as factors responsible for liver steatosis was briefly analyzed. Thus, weight reduction therapy seems to be the major therapeutic approach, and pharmacotherapy seems not to be significantly effective.