XV Konferencja Naukowa Polskiego Towarzystwa Hepatologicznego
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Catch up growth in children with cholestatic syndromes
Joanna Pawłowska, Piotr Socha, Irena Jankowska
Medical Science Review - Hepatologia 2010; 10 101-104
aaICID: 911696
Article type: Review article
IC™ Value: 3.34
Abstract provided by Publisher
Cholestatic liver diseases in childhood frequently result in growth retardation. The pathophysiology is usually multifactoral including reduced calorie intake, abnormal protein metabolism, fat and fat soluble vitamin malabsorption, increased energy expenditure, pancreatic insufficiency, accompanying infections and genetic disposition. All children with cholestatic liver diseases should undergo an assessment for their nutritional status and dietary intake and receive dietary counseling from a dietitian with monitoring of intake to ensure adequate energy and nutrient intake. After liver transplantation growth improves in the majority of children with good liver function. However some children, especially with genetic diseases such as Alagille syndrome, PFIC or CF do not grow normally. In selected cases therapy with growth hormone should be considered.

ICID 911696

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