XV Konferencja Naukowa Polskiego Towarzystwa Hepatologicznego
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Hepatocellular carcinoma – a growing threat. Can it be reduced?
Andrzej Habior
Medical Science Review - Hepatologia 2011; 11 75-80
aaICID: 970952
Article type: Review article
IC™ Value: 3.40
Abstract provided by Publisher
Hepatocellular carcinoma (HCC) is the third most common cause of death from
cancer. The highest incidence of HCC is reported in East Asia and Africa, however in the last
decades the incidence and mortality from HCC are increasing in developed countries in North
America and Europe. These changes of epidemiology of HCC in Western nations result mainly
from growing incidences of HCV infection, high consumption of alcohol and “epidemics” of
metabolic disorders (obesity, diabetes and fatty liver disease).
The prevention of HCC should be complex. It means protection of healthy people from viral
infection (HBV, HCV) by detection of infected patients, improving quality of medical services
and public health measures and vaccinations. In patients with chronic liver diseases with
risk of HCC the prevention of cancer should focus on medical treatment in order to eliminate
of etiologic factor and to slow the progression of the disease. Vaccines and eradication treatments
for prevention infection-caused cancer will continue to reduce morbidity and mortality
from these diseases. National programme of vaccination against HBV in Taiwan was first
in the world and has been introduced 27 years ago. Recently published reports have shown
spectacular results of this kind of primary prevention. In Taiwan, actual incidence of HBV infection
is ten times lower than figure before vaccination programme and the incidence of HCC
dropped almost three times.

ICID 970952

DOI 10.5604/17305039.970952

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